Hidden Organ In Our Eyes Found To Control Circadian Rhythms And Emotions
In the 1920s Harvard University graduate student Clyde E. Keeler discovered two surprising facts about mice he had bred in his rented attic room. One, all the progeny were completely blind. Two, despite the animals’ blindness, their pupils still constricted in response to ambient light, albeit at a slower rate than did the pupils of sighted mice. Many years later researchers extended Keeler’s observation, showing that mice genetically engineered to lack rods and cones (the light receptors involved in vision) nonetheless reacted to changes in light by adjusting their circadian clock—the internal timer that synchronizes hormone activity, body temperature and sleep....